Childhood Brain Stem Glioma

subtype

Identifier: CI-CAN-00004838
Entity page: /cancer/childhood-brain-stem-glioma ↗
Edges: 61

Neighbours: 26 drugs10 trials
Drawn: 36 of 36 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Childhood Brain Stem Glioma investigated in trials for …INVESTIGATED_IN_TRIALSderived26 of 26show fewer
→ investigated in trials for	Temozolomidesmall molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Brain Stem Glioma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Oxaliplatinsmall molecule

Childhood Brain Stem Glioma studied in …STUDIED_INderived10 of 35show all (up to 200)
→ studied in	NCT05857969Phase 1 · recruiting Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling · condition mapped CURATED_BROADER · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06894979Phase 1 · active not recruiting Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma · condition mapped ONTOLOGY_EXACT · 35 trials mapped (3 active)	—	—	Childhood Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00638898Phase 1 · completed Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor · condition mapped CURATED_BROADER · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06000787NA · recruiting MCT for the Harvard/UCSF ROBIN Center · condition mapped ALIAS · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04341311Phase 1 · terminated Phase I Study of Marizomib + Panobinostat for Children With DIPG · condition mapped ALIAS · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03860376completed Ex Vivo Drug Sensitivity Testing and Mutation Profiling · condition mapped CURATED_BROADER · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02415153Phase 1 · completed Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors · condition mapped CURATED_BROADER · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01878266NA · completed Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children · condition mapped ALIAS · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02255461Phase 1 · terminated Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors · condition mapped CURATED_BROADER · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02758366Phase 2 · terminated Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma · condition mapped ALIAS · 35 trials mapped (3 active)	—	—	Childhood Brain Stem Glioma	1	Observed	clinicaltrials	graph →

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