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Knowledge graph · Cancer

Central Nervous System Non-Hodgkin Lymphoma

hematologic malignancy

Identifier: CI-CAN-00002144
Entity page: /cancer/central-nervous-system-non-hodgkin-lymphoma ↗
Edges: 43

Neighbours: 22 drugs10 trials
Drawn: 32 of 32 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Central Nervous System Non-Hodgkin Lymphoma investigated in trials for …INVESTIGATED_IN_TRIALSderived22 of 22show fewer
→ investigated in trials for	Methotrexatesmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Central Nervous System Non-Hodgkin Lymphoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Rituximab

Central Nervous System Non-Hodgkin Lymphoma studied in …STUDIED_INderived10 of 21show all (up to 200)
→ studied in	NCT04609046Phase 1 · active not recruiting Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →
→ studied in	NCT03038672Phase 2 · active not recruiting Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →
→ studied in	NCT07402876Phase 3 · recruiting A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma · condition mapped ALIAS · 21 trials mapped (4 active)	—	—	Primary Vitreoretinal Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05211336Phase 1 · active not recruiting Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →
→ studied in	NCT01588015Phase 1 · completed Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Primary Central Nervous System Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01000753completed Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Central Nervous System Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05950490unknown Construction of Diagnosis and Treatment System for Primary Vitreoretinal Lymphoma · condition mapped ALIAS · 21 trials mapped (4 active)	—	—	Primary Vitreoretinal Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04899453Phase 2 · unknown Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRL · condition mapped ALIAS · 21 trials mapped (4 active)	—	—	Primary Vitreoretinal Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01973062Phase 2 · terminated Yttrium Y 90 Ibritumomab Tiuxetan and Rituximab in Primary Central Nervous System Non-Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Primary Central Nervous System Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00918333Phase 1/Phase 2 · completed Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)	—	—	Primary Central Nervous System Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →

Central Nervous System Non-Hodgkin Lymphoma studied in …STUDIED_INderived10 of 21show all (up to 200)

→ studied in

NCT04609046Phase 1 · active not recruiting

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

→ studied in

NCT03038672Phase 2 · active not recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

→ studied in

NCT07402876Phase 3 · recruiting

A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma · condition mapped ALIAS · 21 trials mapped (4 active)

—

Primary Vitreoretinal Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

→ studied in

NCT05211336Phase 1 · active not recruiting

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

→ studied in

NCT01588015Phase 1 · completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Primary Central Nervous System Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

→ studied in

NCT01000753completed

Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Central Nervous System Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

→ studied in

NCT05950490unknown

Construction of Diagnosis and Treatment System for Primary Vitreoretinal Lymphoma · condition mapped ALIAS · 21 trials mapped (4 active)

—

Primary Vitreoretinal Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

→ studied in

NCT04899453Phase 2 · unknown

Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRL · condition mapped ALIAS · 21 trials mapped (4 active)

—

Primary Vitreoretinal Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

→ studied in

NCT01973062Phase 2 · terminated

Yttrium Y 90 Ibritumomab Tiuxetan and Rituximab in Primary Central Nervous System Non-Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Primary Central Nervous System Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

→ studied in

NCT00918333Phase 1/Phase 2 · completed

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 21 trials mapped (4 active)

—

Primary Central Nervous System Non-Hodgkin Lymphoma

Observed

clinicaltrials

graph →

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