Breast Lobular Carcinoma In Situ — knowledge graph · CancerIndex

Knowledge graph · Cancer

Breast Lobular Carcinoma In Situ

subtype

Identifier: CI-CAN-00000608
Entity page: /cancer/breast-lobular-carcinoma-in-situ ↗
Edges: 49

Neighbours: 8 drugs10 trials
Drawn: 18 of 18 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Breast Lobular Carcinoma In Situ investigated in trials for …INVESTIGATED_IN_TRIALSderived8 of 8
→ investigated in trials for	Tamoxifensmall molecule 7 trials (3 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma In Situ	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Letrozolesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants

Breast Lobular Carcinoma In Situ studied in …STUDIED_INderived10 of 41show all (up to 200)
→ studied in	NCT04570956Phase 2 · terminated Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT07408856Phase 1 · recruiting CAN1012 in Pre-Malignant DCIS and LCIS · condition mapped ALIAS · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT06033092Phase 2 · completed Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion · condition mapped ALIAS · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT03317405Phase 1 · active not recruiting Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT06671912Phase 3 · suspended Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT06195306Phase 2 · recruiting Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT06184750Phase 2 · recruiting Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT05941520Phase 2 · recruiting Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT02515110NA · active not recruiting Hypofractionated Regional Nodal Irradiation Clinical Trial for Women With Breast Cancer · condition mapped ALIAS · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT05178498recruiting Impact of Dietary Inflammatory Potential on Breast Cancer Risk · condition mapped ONTOLOGY_EXACT · 41 trials mapped (11 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →