Autonomic Nervous System Neoplasm

subtype

Identifier: CI-CAN-00000468
Entity page: /cancer/autonomic-nervous-system-neoplasm ↗
Edges: 279

Neighbours: 15 genes15 drugs10 trials
Drawn: 40 of 40 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Autonomic Nervous System Neoplasm altered in cohorts of …ALTERED_INderived15 of 99show all (up to 200)
← altered in cohorts of	AMY1A 128 / 179 cases (72 %) · ssm · TCGA-PCPG	—	—	Paraganglioma	1	Observed	gdc	graph →
← altered in cohorts of	AMY1B 128 / 179 cases (72 %) · ssm · TCGA-PCPG	—

Autonomic Nervous System Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 32show all (up to 200)
→ investigated in trials for	Temozolomidesmall molecule 5 trials (1 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Everolimussmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Axitinibsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Cabozantinibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ifosfamidesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Lutetium (177lu) Oxodotreotideother 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Sunitinibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostatsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Belzutifansmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Capecitabinesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Autonomic Nervous System Neoplasm	1	Observed	clinicaltrials	graph →

Autonomic Nervous System Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 32show all (up to 200)

→ investigated in trials for

Temozolomidesmall molecule

5 trials (1 active) · roll-up of the cancer and its descendants

—

Autonomic Nervous System Neoplasm

Observed

Autonomic Nervous System Neoplasm studied in …STUDIED_INderived10 of 148show all (up to 200)
→ studied in	NCT00004847Phase 1 · recruiting Diagnosis of Pheochromocytoma · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07743138Phase 2 · not yet recruiting STOMP OUT: A Phase 2 Study To Evaluate The Effects Of Ivonescimab In Patients With Unresectable/Metastatic Adrenocortical Carcinoma (ACC) Or Unresectable Pheochromocytoma/Paraganglioma (PPGL) · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04394858Phase 2 · active not recruiting Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer · condition mapped CURATED_BROADER · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02402244recruiting Project: Every Child for Younger Patients With Cancer · condition mapped ONTOLOGY_EXACT · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03206060Phase 2 · recruiting Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07784595NA · not yet recruiting Comparison of an Initial Active Follow-up and Therapeutic Care on Functional Outcome and Quality of Life in Patients With Head and Neck Paragangliomas · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Paraganglioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06427798Phase 1/Phase 2 · recruiting Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06377033NA · recruiting Using the EHR to Advance Genomic Medicine Across a Diverse Health System · condition mapped ONTOLOGY_EXACT · 148 trials mapped (50 active)	—	—	Paraganglioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03015844available A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07714551Phase 2 · not yet recruiting Zanzalintinib in Unresectable and Progressive MPGGs · condition mapped ALIAS · 148 trials mapped (50 active)	—	—	Adrenal Gland Pheochromocytoma	1	Observed	clinicaltrials	graph →

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