Anal Canal Squamous Cell Carcinoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Anal Canal Squamous Cell Carcinoma

subtype

Identifier: CI-CAN-00004455
Entity page: /cancer/anal-canal-squamous-cell-carcinoma ↗
Edges: 16

Neighbours: 8 drugs8 trials
Drawn: 16 of 16 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Anal Canal Squamous Cell Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived8 of 8
→ investigated in trials for	Fluorouracilsmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Anal Canal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 3 trials (3 active) · roll-up of the cancer and its descendants

Anal Canal Squamous Cell Carcinoma studied in …STUDIED_INderived8 of 8
→ studied in	NCT02314169Phase 2 · active not recruiting Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04166318Phase 2 · active not recruiting Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04444921Phase 3 · active not recruiting EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Cloacogenic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03233711Phase 3 · active not recruiting Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Cloacogenic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03712566active not recruiting Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03690921Phase 2 · completed Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02560298Phase 2 · unknown Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Cloacogenic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04499352Phase 2 · withdrawn A Study to Test BI 754091 Alone or in Combination With BI 836880 in People Who Have Advanced Anal Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (5 active)	—	—	Anal Canal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →