Adult Glioblastoma

subtype

Identifier: CI-CAN-00001730
Entity page: /cancer/adult-glioblastoma ↗
Edges: 188

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Adult Glioblastoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 49show all (up to 200)
→ investigated in trials for	Temozolomidesmall molecule 27 trials (5 active) · roll-up of the cancer and its descendants	—	—	Adult Glioblastoma	27	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody

Adult Glioblastoma studied in …STUDIED_INderived10 of 139show all (up to 200)
→ studied in	NCT03277638Phase 1/Phase 2 · completed Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM) · condition mapped ONTOLOGY_EXACT · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02974738Phase 1 · active not recruiting A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) · condition mapped ONTOLOGY_EXACT · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05052957Phase 2 · recruiting hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) · condition mapped ALIAS · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02142803Phase 1 · active not recruiting TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors · condition mapped ONTOLOGY_EXACT · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06954636recruiting Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study · condition mapped ALIAS · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00268385Phase 1 · active not recruiting Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas · condition mapped ONTOLOGY_EXACT · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06614855Phase 1 · active not recruiting A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma · condition mapped ONTOLOGY_EXACT · 139 trials mapped (28 active)	—	—	Adult Gliosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07100730Phase 3 · recruiting Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma · condition mapped ALIAS · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06991101Phase 2 · recruiting Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma · condition mapped ALIAS · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05720078NA · active not recruiting UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-3 (UNITED-3) · condition mapped ALIAS · 139 trials mapped (28 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →

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