Gene
ZNF777
zinc finger protein 777
Explore in graph →CI-GENE-00040070HGNC:22213 ENSG00000196453 NCBI 27153 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Refractory Cancers (RC) - Peripheral T-Cell Lymphoma (PTCL) RC-PTCL | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Ssm | 15 | 58 | 25.9% | 56 | gdc |
| Thyroid Carcinoma (TCGA, Firehose Legacy) thca_tcga | Thyroid Gland Papillary Carcinoma | Ssm | 3 | 405 | 0.7% | 191 | cbioportal |
| Papillary Thyroid Carcinoma (TCGA, Cell 2014) thca_tcga_pub | Thyroid Gland Papillary Carcinoma | Ssm | 3 | 496 | 0.6% | 185 | cbioportal |
| Papillary Thyroid Cancer (TCGA GDC, 2025) thpa_tcga_gdc | Thyroid Gland Papillary Carcinoma | Ssm | 3 | 496 | 0.6% | 133 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.