Gene
ZNF681
zinc finger protein 681
Explore in graph →CI-GENE-00039979HGNC:26457 ENSG00000196172 NCBI 148213 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25765070
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Adenocarcinoma (MSK, Science 2015) luad_mskcc_2015 | Lung Adenocarcinoma | Ssm | 5 | 35 | 14.3% | 86 | cbioportal |
| Bladder Urothelial Carcinoma (DFCI/MSK, Cancer Discov 2014) blca_dfarber_mskcc_2014 | Bladder Urothelial Carcinoma | Ssm | 6 | 50 | 12% | 82 | cbioportal |
| Pediatric Pan-cancer (Columbia U, Genome Med 2016) mixed_pipseq_2017 | unmapped | Ssm | 10 | 103 | 9.7% | 151 | cbioportal |
| Pediatric Brain Cancer (CPTAC/CHOP, Cell 2020) brain_cptac_2020 | unmapped | Ssm | 10 | 218 | 4.6% | 69 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.