Gene
ZNF678
zinc finger protein 678
Explore in graph →CI-GENE-00039975HGNC:28652 ENSG00000181450 NCBI 339500 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24487277
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Clear Cell Carcinoma (IRC, Nat Genet 2014) ccrcc_irc_2014 | Clear Cell Renal Cell Carcinoma | Ssm | 8 | 78 | 10.3% | 180 | cbioportal |
| Pancreatic Neuroendocrine Tumors (Johns Hopkins University, Science 2011) panet_jhu_2011 | Pancreatic Neuroendocrine Tumor | Ssm | 1 | 10 | 10% | 142 | cbioportal |
| Wilms' Tumor (TARGET GDC, 2025) wt_target_gdc | Wilms Tumor | Ssm | 2 | 42 | 4.8% | 32 | cbioportal |
| Pediatric Brain Cancer (CPTAC/CHOP, Cell 2020) brain_cptac_2020 | unmapped | Ssm | 9 | 218 | 4.1% | 85 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.