Gene
WNK3
WNK lysine deficient protein kinase 3
Explore in graph →CI-GENE-00038884HGNC:14543 ENSG00000196632 NCBI 65267 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22561520
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cholangiocarcinoma (National University of Singapore, Nat Genet 2012) chol_nus_2012 | Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 179 | cbioportal |
| Cervical Squamous Cell Carcinoma (TCGA GDC, 2025) cesc_tcga_gdc | Cervical Squamous Cell Carcinoma | Ssm | 16 | 289 | 5.5% | 83 | cbioportal |
| Cervical Squamous Cell Carcinoma (TCGA, PanCancer Atlas) cesc_tcga_pan_can_atlas_2018 | Cervical Squamous Cell Carcinoma | Ssm | 15 | 291 | 5.2% | 139 | cbioportal |
| Triple-Negative Breast Cancer (FUSCC, Cell Research 2020) brca_fuscc_2020 | Invasive Breast Carcinoma | Ssm | 3 | 69 | 4.3% | 67 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.