Gene
WAS
WASP actin nucleation promoting factor
Explore in graph →CI-GENE-00038690HGNC:12731 ENSG00000015285 NCBI 7454 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25092538
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Bladder Cancer (MSK, Eur Urol 2014) blca_mskcc_solit_2014 | Bladder Urothelial Carcinoma | Ssm | 5 | 109 | 4.6% | 57 | cbioportal |
| Metastatic Melanoma (MSK, JCO Precis Oncol 2017) skcm_vanderbilt_mskcc_2015 | Cutaneous Melanoma | Ssm | 2 | 66 | 3% | 139 | cbioportal |
| Medulloblastoma (Broad, Nature 2012) mbl_broad_2012 | Medulloblastoma | Ssm | 2 | 92 | 2.2% | 88 | cbioportal |
| Prostate Adenocarcinoma (MSK, Cancer Cell 2010) prad_mskcc | Prostate Adenocarcinoma | Ssm | 1 | 106 | 0.9% | 123 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.