Gene
USP28
ubiquitin specific peptidase 28
Explore in graph →CI-GENE-00038220HGNC:12625 ENSG00000048028 NCBI 57646 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25608663
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Intrahepatic Cholangiocarcinoma (Mount Sinai 2015) ihch_ismms_2015 | Intrahepatic Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 128 | cbioportal |
| Comparison of Cutaneous Sarcomas, CSCC and Deeper Sarcomas (DFCI, 2026) sarcoma_dfci_genie_2026 | unmapped | Ssm | 4 | 48 | 8.3% | 144 | cbioportal |
| Prostate Adenocarcinoma (Fred Hutchinson CRC, Nat Med 2016) prad_fhcrc | Prostate Adenocarcinoma | Ssm | 9 | 141 | 6.4% | 121 | cbioportal |
| Metastatic Prostate Adenocarcinoma (MCTP, Nature 2012) prad_mich | Prostate Adenocarcinoma | Ssm | 3 | 61 | 4.9% | 123 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.