Gene
UBE4A
ubiquitination factor E4A
Explore in graph →CI-GENE-00037836HGNC:12499 ENSG00000110344 NCBI 9354 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 2 | 4 | 50% | 80 | cbioportal |
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 12 | 116 | 10.3% | 169 | cbioportal |
| Liposarcoma (MSK, 2026) lipo_msk_2026 | Liposarcoma | Ssm | 4 | 277 | 1.4% | 80 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.