Gene
TPRX1
tetrapeptide repeat homeobox 1
Explore in graph →CI-GENE-00036001HGNC:32174 ENSG00000178928 NCBI 284355 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 35504881
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Cancer Brain Metastases (Bern, Nat Commun. 2022) prostate_pcbm_swiss_2019 | unmapped | Ssm | 14 | 168 | 8.3% | 72 | cbioportal |
| Triple-Negative Breast Cancer (FUSCC, Cell Research 2020) brca_fuscc_2020 | Invasive Breast Carcinoma | Ssm | 2 | 69 | 2.9% | 138 | cbioportal |
| Pediatric Brain Cancer (CPTAC/CHOP, Cell 2020) brain_cptac_2020 | unmapped | Ssm | 6 | 218 | 2.8% | 185 | cbioportal |
| Acute Myeloid Leukemia (OHSU, Cancer Cell 2022) aml_ohsu_2022 | Acute Myeloid Leukemia | Ssm | 10 | 903 | 1.1% | 42 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.