Gene
TMEM127
transmembrane protein 127
Explore in graph →CI-GENE-00035477HGNC:26038 ENSG00000135956 NCBI 55654 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 41758938
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Soft Tissue Sarcoma MYOD1 (MSK, Sci Adv 2026) soft_tissue_myod1_msk_2025 | Rhabdomyosarcoma | Ssm | 1 | 20 | 5% | 37 | cbioportal |
| Lung Adenocarcinoma (MSK, 2021) luad_mskimpact_2021 | Lung Adenocarcinoma | Ssm | 2 | 186 | 1.1% | 132 | cbioportal |
| Uterine Sarcoma/Mesenchymal (MSK, Clin Cancer Res 2020) usarc_msk_2020 | Uterine Corpus Sarcoma | Ssm | 1 | 108 | 0.9% | 148 | cbioportal |
| Poorly-Differentiated and Anaplastic Thyroid Cancers (MSK, JCI 2016) thyroid_mskcc_2016 | unmapped | Ssm | 1 | 117 | 0.9% | 179 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.