Gene
TJP3
tight junction protein 3
Explore in graph →CI-GENE-00035229HGNC:11829 ENSG00000105289 NCBI 27134 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24336570
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Low-Grade Gliomas (UCSF, Science 2014) lgg_ucsf_2014 | Diffuse Glioma | Ssm | 5 | 61 | 8.2% | 81 | cbioportal |
| Acute Myeloid Leukemia (TARGET GDC, 2025) aml_target_gdc | Acute Myeloid Leukemia | Ssm | 4 | 584 | 0.7% | 64 | cbioportal |
| Pediatric Neuroblastoma (TARGET, 2018) nbl_target_2018_pub | Neuroblastoma | Ssm | 1 | 1,089 | 0.1% | 142 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.