Gene
TIAM2
TIAM Rac1 associated GEF 2
Explore in graph →CI-GENE-00035150HGNC:11806 ENSG00000146426 NCBI 26230 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25233892
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Uterine Carcinosarcoma (Johns Hopkins, Nat Commun 2014) ucs_jhu_2014 | Uterine Malignant Mixed Mesodermal (Mullerian) Tumor | Ssm | 4 | 22 | 18.2% | 155 | cbioportal |
| Lymphoid Neoplasm Diffuse Large B-cell Lymphoma (TCGA, Firehose Legacy) dlbc_tcga | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 5 | 48 | 10.4% | 104 | cbioportal |
| Pancreatic Adenocarcinoma (TCGA, Firehose Legacy) paad_tcga | Pancreatic Adenocarcinoma | Ssm | 5 | 150 | 3.3% | 169 | cbioportal |
| Prostate Adenocarcinoma (TCGA GDC, 2025) prad_tcga_gdc | Prostate Adenocarcinoma | Ssm | 6 | 491 | 1.2% | 182 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.