Gene
TBC1D1
TBC1 domain family member 1
Explore in graph →CI-GENE-00034617HGNC:11578 ENSG00000065882 NCBI 23216 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28485815
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017 | Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type | Ssm | 2 | 16 | 12.5% | 58 | cbioportal |
| Combined Hepatocellular and Intrahepatic Cholangiocarcinoma (Peking University, Cancer Cell 2019) hccihch_pku_2019 | Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Ssm | 7 | 173 | 4% | 104 | cbioportal |
| Breast Invasive Carcinoma (Sanger, Nature 2012) brca_sanger | Invasive Breast Carcinoma | Ssm | 3 | 100 | 3% | 176 | cbioportal |
| Pediatric Pan-Cancer (DKFZ, Nature 2017) pediatric_dkfz_2017 | unmapped | Ssm | 5 | 876 | 0.6% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.