Gene
SOX5
SRY-box transcription factor 5
Explore in graph →CI-GENE-00033347HGNC:11201 ENSG00000134532 NCBI 6660 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25583476
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Gastric Adenocarcinoma (TMUCIH, PNAS 2015) egc_tmucih_2015 | Gastroesophageal Junction Adenocarcinoma | Ssm | 5 | 78 | 6.4% | 148 | cbioportal |
| Esophageal Adenocarcinoma (DFCI, Nat Genet 2013) esca_broad | Esophageal Adenocarcinoma | Ssm | 9 | 151 | 6% | 157 | cbioportal |
| Pancreatic Cancer (UTSW, Nat Commun 2015) paad_utsw_2015 | Pancreatic Adenocarcinoma | Ssm | 4 | 109 | 3.7% | 160 | cbioportal |
| Pancreatic Adenocarcinoma (ICGC, Nature 2012) paad_icgc | Pancreatic Adenocarcinoma | Ssm | 2 | 99 | 2% | 121 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.