Gene
SMG7
SMG7 nonsense mediated mRNA decay factor
Explore in graph →CI-GENE-00031452HGNC:16792 ENSG00000116698 NCBI 9887 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 37406106
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Esophagogastric Cancer (MSK, Clin Cancer Res 2023) egc_trap_ccr_msk_2023 | Gastroesophageal Junction Adenocarcinoma | Ssm | 6 | 64 | 9.4% | 92 | cbioportal |
| Kidney Renal Clear Cell Carcinoma (TCGA, Firehose Legacy) kirc_tcga | Clear Cell Renal Cell Carcinoma | Ssm | 16 | 451 | 3.5% | 112 | cbioportal |
| Acute Myeloid Leukemia (TCGA, PanCancer Atlas) laml_tcga_pan_can_atlas_2018 | Acute Myeloid Leukemia | Ssm | 4 | 200 | 2% | 138 | cbioportal |
| Prostate Adenocarcinoma (TCGA, Firehose Legacy) prad_tcga | Prostate Adenocarcinoma | Ssm | 8 | 499 | 1.6% | 198 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.