Gene
SLIT1
slit guidance ligand 1
Explore in graph →CI-GENE-00031341HGNC:11085 ENSG00000187122 NCBI 6585 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25765070
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Adenocarcinoma (MSK, Science 2015) luad_mskcc_2015 | Lung Adenocarcinoma | Ssm | 4 | 35 | 11.4% | 176 | cbioportal |
| Esophageal Cancer-TRAP Project (MSK, Lancet Oncol 2020) egc_trap_msk_2020 | Gastroesophageal Junction Adenocarcinoma | Ssm | 3 | 31 | 9.7% | 123 | cbioportal |
| Head and Neck Carcinoma, Other (CPTAC GDC, 2025) ohnca_cptac_gdc | Head and Neck Carcinoma, Other | Ssm | 7 | 108 | 6.5% | 184 | cbioportal |
| Testicular Germ Cell Cancer (TCGA, Firehose Legacy) tgct_tcga | Non-Seminomatous Germ Cell Tumor | Ssm | 5 | 155 | 3.2% | 90 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.