Gene
SLC6A3
solute carrier family 6 member 3
Explore in graph →CI-GENE-00030822HGNC:11049 ENSG00000142319 NCBI 6531 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial ALCHEMIST-ALCH | unmapped | Ssm | 470 | 1,170 | 40.2% | 33 | gdc |
| Brain Lower Grade Glioma (TCGA, Firehose Legacy) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.