Gene
SESN3
sestrin 3
Explore in graph →CI-GENE-00030388HGNC:23060 ENSG00000149212 NCBI 143686 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (12)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 38653864
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Endometrial and Ovarian Cancer (MSK, Nature Medicine 2024) ucec_msk_2024 | unmapped | Ssm | 4 | 31 | 12.9% | 116 | cbioportal |
| Pleural Mesothelioma (MSK, Clin Cancer Res 2024) plmeso_msk_2024 | Pleural Mesothelial Neoplasm | Ssm | 1 | 12 | 8.3% | 32 | cbioportal |
| Rectal Cancer (MSK,Nature Medicine 2019) rectal_msk_2019 | Colorectal Adenocarcinoma | Ssm | 4 | 49 | 8.2% | 196 | cbioportal |
| Pancreatic Neuroendocrine Tumors (MSK, 2023) panet_msk_erc_2023 | unmapped | Ssm | 3 | 59 | 5.1% | 41 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.