Gene
SEMA5B
semaphorin 5B
Explore in graph →CI-GENE-00030221HGNC:10737 ENSG00000082684 NCBI 54437 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adrenocortical Carcinoma (TCGA, Firehose Legacy) acc_tcga | Adrenal Cortical Carcinoma | Ssm | 16 | 90 | 17.8% | 41 | cbioportal |
| Colorectal Adenocarcinoma (Genentech, Nature 2012) coadread_genentech | Colorectal Adenocarcinoma | Ssm | 9 | 72 | 12.5% | 143 | cbioportal |
| Adenoid Cystic Carcinoma of the Breast (MSK, J Pathol. 2015) acbc_mskcc_2015 | Breast Adenoid Cystic Carcinoma | Ssm | 1 | 12 | 8.3% | 122 | cbioportal |
| Combined Hepatocellular and Intrahepatic Cholangiocarcinoma (Peking University, Cancer Cell 2019) hccihch_pku_2019 | Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Ssm | 7 | 173 | 4% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.