Gene
SEMA3C
semaphorin 3C
Explore in graph →CI-GENE-00030204HGNC:10725 ENSG00000075223 NCBI 10512 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (8)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26829750
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma (MGH, Nat Gen 2016) acyc_mgh_2016 | Adenoid Cystic Carcinoma | Ssm | 2 | 10 | 20% | 149 | cbioportal |
| Diffuse Large B-Cell Lymphoma, NOS (TCGA GDC, 2025) dlbclnos_tcga_gdc | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 3 | 36 | 8.3% | 132 | cbioportal |
| Diffuse Large B-Cell Lymphoma (TCGA, PanCancer Atlas) dlbc_tcga_pan_can_atlas_2018 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 3 | 41 | 7.3% | 186 | cbioportal |
| Glioblastoma Multiforme (TCGA, Firehose Legacy) gbm_tcga | Diffuse Glioma | Ssm | 11 | 290 | 3.8% | 63 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.