Gene
RPS6KB2
ribosomal protein S6 kinase B2
Explore in graph →CI-GENE-00028930HGNC:10437 ENSG00000175634 NCBI 6199 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (13)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28007021
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pediatric Pan-cancer (Columbia U, Genome Med 2016) mixed_pipseq_2017 | unmapped | Ssm | 10 | 103 | 9.7% | 146 | cbioportal |
| Disparities in metastatic colorectal cancer between Africans and Americans (MSK, 2020) crc_nigerian_2020 | Colorectal Adenocarcinoma | Ssm | 3 | 64 | 4.7% | 168 | cbioportal |
| Endometrial cancer HR-positive (MSK, 2024) uec_msk_2024 | Endometrial Carcinoma | Ssm | 1 | 24 | 4.2% | 112 | cbioportal |
| Gallbladder Cancer (MSK, Cancer 2018) gbc_msk_2018 | Gallbladder Carcinoma | Ssm | 4 | 103 | 3.9% | 38 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.