Gene
RPS6KA4
ribosomal protein S6 kinase A4
Explore in graph →CI-GENE-00028926HGNC:10433 ENSG00000162302 NCBI 8986 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (62)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32220891
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic castration-sensitive prostate cancer (MSK, Clin Cancer Res 2020) prad_mcspc_mskcc_2020 | Prostate Adenocarcinoma | Ssm | 3 | 424 | 0.7% | 189 | cbioportal |
| Prostate Cancer (MSK, JCO Precis Oncol 2017) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.