Gene
REC8
REC8 meiotic recombination protein
Explore in graph →CI-GENE-00023294HGNC:16879 ENSG00000100918 NCBI 9985 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 23685749
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma (MSK, Nat Genet 2013) acyc_mskcc_2013 | Adenoid Cystic Carcinoma | Ssm | 2 | 60 | 3.3% | 30 | cbioportal |
| Uveal Melanoma (TCGA, Firehose Legacy) uvm_tcga | Uveal Melanoma | Ssm | 2 | 80 | 2.5% | 81 | cbioportal |
| Pilocytic Astrocytoma (ICGC, Nature Genetics 2013) past_dkfz_heidelberg_2013 | Pilocytic Astrocytoma | Ssm | 1 | 96 | 1% | 114 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.