Gene
RCSD1
RCSD domain containing 1
Explore in graph →CI-GENE-00023270HGNC:28310 ENSG00000198771 NCBI 92241 Cancer geneApproved
Curated evidence
Clinical evidence (1)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 27125982
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| RCSD1 RCSD1::ABL11 | ||||||||
| Imatinib | Childhood B-cell Acute Lymphoblastic LeukemiaUNRESOLVED | Predictive | C | Supports Sensitivity Response | 3 | rejected | EID7782In the case report, it has been stated that the patient with known B-cell precursor ALL was induced to remission by imatinib, a tyrosine kinase inhibitor that affects the following eight ABL1 fusion p… (full text at CIViC) PMID 27125982 · Perwein et al., 2016 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (1)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Burkitt Lymphoma Genome Sequencing Project CGCI-BLGSP | Burkitt Lymphoma | Ssm |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.