Gene
RAPGEF6
Rap guanine nucleotide exchange factor 6
Explore in graph →CI-GENE-00022961HGNC:20655 ENSG00000158987 NCBI 51735 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26950094
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Basal Cell Carcinoma (UNIGE, Nat Genet 2016) bcc_unige_2016 | Skin Basal Cell Carcinoma | Ssm | 52 | 293 | 17.7% | 128 | cbioportal |
| Gastric Cancer (OncoSG, 2018) stad_oncosg_2018 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.