Gene
RABL3
RAB, member of RAS oncogene family like 3
Explore in graph →CI-GENE-00022821HGNC:18072 ENSG00000144840 NCBI 285282 CIViC Approved
Curated evidence
Clinical evidence (1)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 31406347
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| RABL3 MUTATION1 | ||||||||
| (predisposing) | Malignant Pancreatic Neoplasm | Predisposing | C | Supports Pathogenic | 3 | submitted | EID7497Whole-genome sequence analysis in a family with multiple cases of pancreatic ductal adenocarcinoma identified a germline RABL3 truncating mutation. RABL3 was associated with the regulation of the pren… (full text at CIViC) PMID 31406347 · Nissim et al., 2019 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (0)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
Data not yet available
No cohort frequency recorded for this gene.
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.