Gene
PTGS1
prostaglandin-endoperoxide synthase 1
Explore in graph →CI-GENE-00022449HGNC:9604 ENSG00000095303 NCBI 5742 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26829750
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma (MGH, Nat Gen 2016) acyc_mgh_2016 | Adenoid Cystic Carcinoma | Ssm | 2 | 10 | 20% | 140 | cbioportal |
| Solitary Fibrous Tumors (SYSUCC, Nat Commun 2023) sft_sysucc_2023 | unmapped | Ssm | 3 | 131 | 2.3% | 144 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, PanCancer Atlas) pcpg_tcga_pan_can_atlas_2018 | unmapped | Ssm | 2 | 178 | 1.1% | 96 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, Cell 2017) pcpg_tcga_pub | unmapped | Ssm | 2 | 178 | 1.1% | 180 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.