Gene
PRDM16
PR/SET domain 16
Explore in graph →CI-GENE-00020894HGNC:14000 ENSG00000142611 NCBI 63976 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25991819
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Primary Central Nervous System Lymphoma (Mayo Clinic, Clin Cancer Res 2015) pcnsl_mayo_2015 | Primary Central Nervous System Lymphoma | Ssm | 2 | 10 | 20% | 74 | cbioportal |
| Melanoma (MSK, Cell 2017) - iAtlas Harmonized mel_iatlas_riaz_nivolumab_2017 | Melanoma | Ssm | 9 | 73 | 12.3% | 109 | cbioportal |
| Urothelial Carcinoma (BCAN/HCRN, Nat Commun 2022) blca_bcan_hcrn_2022 | Bladder Urothelial Carcinoma | Ssm | 12 | 192 | 6.3% | 99 | cbioportal |
| Proteogenomic landscape of breast cancer (CPTAC, Cell 2020) brca_cptac_2020 | Invasive Breast Carcinoma | Ssm | 7 | 122 | 5.7% | 66 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.