Gene
PRB4
proline rich protein BstNI subfamily 4
Explore in graph →CI-GENE-00020866HGNC:9340 ENSG00000230657 NCBI 5545 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28007021
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pediatric Pan-cancer (Columbia U, Genome Med 2016) mixed_pipseq_2017 | unmapped | Ssm | 9 | 103 | 8.7% | 176 | cbioportal |
| Pediatric Brain Cancer (CPTAC/CHOP, Cell 2020) brain_cptac_2020 | unmapped | Ssm | 15 | 218 | 6.9% | 19 | cbioportal |
| Pancreatic Cancer (UTSW, Nat Commun 2015) paad_utsw_2015 | Pancreatic Adenocarcinoma | Ssm | 5 | 109 | 4.6% | 70 | cbioportal |
| Prostate Adenocarcinoma (CPC-GENE, Nature 2017) prad_cpcg_2017 | Prostate Adenocarcinoma | Ssm | 9 | 477 | 1.9% | 8 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.