Gene
PHACTR1
phosphatase and actin regulator 1
Explore in graph →CI-GENE-00019559HGNC:20990 ENSG00000112137 NCBI 221692 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Clear Cell Carcinoma (TCGA, Firehose Legacy) kirc_tcga | Clear Cell Renal Cell Carcinoma | Ssm | 21 | 451 | 4.7% | 36 | cbioportal |
| Pancreatic Adenocarcinoma (TCGA GDC, 2025) paad_tcga_gdc | Pancreatic Adenocarcinoma |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.