Gene
PDE4D
phosphodiesterase 4D
Explore in graph →CI-GENE-00019235HGNC:8783 ENSG00000113448 NCBI 5144 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25608663
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Intrahepatic Cholangiocarcinoma (Mount Sinai 2015) ihch_ismms_2015 | Intrahepatic Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 88 | cbioportal |
| Nerve Sheath Tumors (Johns Hopkins, 2024) nst_nfosi_ntap | Nerve Sheath Neoplasm | Ssm | 5 | 80 | 6.3% | 145 | cbioportal |
| Metastatic Breast Cancer (INSERM, PLoS Med 2016) brca_igr_2015 | Invasive Breast Carcinoma | Ssm | 6 | 216 | 2.8% | 187 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.