Gene
PCDHB3
protocadherin beta 3
Explore in graph →CI-GENE-00019060HGNC:8688 ENSG00000113205 NCBI 56132 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25991819
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Primary Central Nervous System Lymphoma (Mayo Clinic, Clin Cancer Res 2015) pcnsl_mayo_2015 | Primary Central Nervous System Lymphoma | Ssm | 2 | 10 | 20% | 69 | cbioportal |
| Melanoma (Broad/Dana Farber, Nature 2012) skcm_broad_dfarber | Cutaneous Melanoma | Ssm | 5 | 26 | 19.2% | 116 | cbioportal |
| Esophageal Adenocarcinoma (TCGA, PanCancer Atlas) esca_tcga_pan_can_atlas_2018 | Esophageal Adenocarcinoma | Ssm | 10 | 182 | 5.5% | 138 | cbioportal |
| Esophageal Adenocarcinoma (TCGA GDC, 2025) esca_tcga_gdc | Esophageal Adenocarcinoma | Ssm | 10 | 185 | 5.4% | 103 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.