Gene
PCDHB1
protocadherin beta 1
Explore in graph →CI-GENE-00019057HGNC:8680 ENSG00000171815 NCBI 29930 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26343386
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Desmoplastic Melanoma (Broad Institute, Nat Genet 2015) desm_broad_2015 | Desmoplastic Melanoma | Ssm | 8 | 20 | 40% | 93 | cbioportal |
| Melanoma (MSK, NEJM 2014) skcm_mskcc_2014 | Cutaneous Melanoma | Ssm | 12 | 64 | 18.8% | 156 | cbioportal |
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 12 | 116 | 10.3% | 142 | cbioportal |
| Pediatric solid tumor PDXs (UTHSA, Nat Commun 2023) pancan_pdx_uthsa_2023 | unmapped | Ssm | 2 | 92 | 2.2% | 183 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.