Gene
OVOL2
ovo like zinc finger 2
Explore in graph →CI-GENE-00018674HGNC:15804 ENSG00000125850 NCBI 58495 CIViC Approved
Curated evidence
Clinical evidence (1)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 34117242
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| OVOL2 Overexpression1 | ||||||||
| Cisplatin | Glandular Pattern Ovarian Yolk Sac TumorUNRESOLVED | Predictive | D | Supports Resistance | 4 | submitted | EID12064RNA-seq data was generated for 12 Yolk Sac Tumour (YST) samples, including 3 sensitive primary tumours and 9 relapsed tumours. Analysis revealed that OVOL2 expression was significantly higher in relap… (full text at CIViC) PMID 34117242 · Zong et al., 2021 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (0)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
Data not yet available
No cohort frequency recorded for this gene.
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.