Gene
NPR2
natriuretic peptide receptor 2
Explore in graph →CI-GENE-00017153HGNC:7944 ENSG00000159899 NCBI 4882 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25470049
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 16 | 116 | 13.8% | 30 | cbioportal |
| Cholangiocarcinoma (TCGA, PanCancer Atlas) chol_tcga_pan_can_atlas_2018 | Cholangiocarcinoma | Ssm | 2 | 36 | 5.6% | 98 | cbioportal |
| Testicular Germ Cell Cancer (TCGA, Firehose Legacy) tgct_tcga | Non-Seminomatous Germ Cell Tumor | Ssm | 4 | 155 | 2.6% | 169 | cbioportal |
| Testicular Germ Cell Tumors (TCGA, PanCancer Atlas) tgct_tcga_pan_can_atlas_2018 | unmapped | Ssm | 2 | 149 | 1.3% | 136 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.