Gene
NPHP3
nephrocystin 3
Explore in graph →CI-GENE-00017060HGNC:7907 ENSG00000113971 NCBI 27031 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22802077
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| NCI-60 Cell Lines (NCI, Cancer Res 2012) cellline_nci60 | unmapped | Ssm | 10 | 60 | 16.7% | 163 | cbioportal |
| Renal Clear Cell Carcinoma (TCGA GDC, 2025) ccrcc_tcga_gdc | Clear Cell Renal Cell Carcinoma | Ssm | 9 | 375 | 2.4% | 64 | cbioportal |
| Wilms' Tumor (TARGET GDC, 2025) wt_target_gdc | Wilms Tumor | Ssm | 1 | 42 | 2.4% | 180 | cbioportal |
| Kidney Renal Clear Cell Carcinoma (TCGA, PanCancer Atlas) kirc_tcga_pan_can_atlas_2018 | Clear Cell Renal Cell Carcinoma | Ssm | 8 | 402 | 2% | 107 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.