Gene
NLRC5
NLR family CARD domain containing 5
Explore in graph →CI-GENE-00016852HGNC:29933 ENSG00000140853 NCBI 84166 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22802077
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| NCI-60 Cell Lines (NCI, Cancer Res 2012) cellline_nci60 | unmapped | Ssm | 17 | 60 | 28.3% | 70 | cbioportal |
| Bladder Urothelial Carcinoma (DFCI/MSK, Cancer Discov 2014) blca_dfarber_mskcc_2014 | Bladder Urothelial Carcinoma | Ssm | 5 | 50 | 10% | 127 | cbioportal |
| Classical Hodgkins Lymphoma (SCCC, Blood Cancer Discov 2023) chl_sccc_2023 | Classic Hodgkin Lymphoma | Ssm | 4 | 61 | 6.6% | 96 | cbioportal |
| Prostate Adenocarcinoma (SMMU, Eur Urol 2017) prad_eururol_2017 | Prostate Adenocarcinoma | Ssm | 2 | 65 | 3.1% | 54 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.