Gene
NFE2
nuclear factor, erythroid 2
Explore in graph →CI-GENE-00016671HGNC:7780 ENSG00000123405 NCBI 4778 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24325359
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Myeloproliferative Neoplasms (CIMR, NEJM 2013) mpn_cimr_2013 | Myeloproliferative Neoplasm | Ssm | 2 | 151 | 1.3% | 47 | cbioportal |
| Myelodysplastic Syndromes (MDS IWG, IPSSM, NEJM Evidence 2022) mds_iwg_2022 | Myelodysplastic Syndrome | Ssm | 43 | 3,323 | 1.3% | 77 | cbioportal |
| Acute Myeloid Leukemia (OHSU, Cancer Cell 2022) aml_ohsu_2022 | Acute Myeloid Leukemia | Ssm | 7 | 903 | 0.8% | 63 | cbioportal |
| Histiocytic and Dendritic Cell Neoplasms (MSK, 2025) hdcn_msk_2025 | Histiocytic and Dendritic Cell Neoplasm | Ssm | 1 | 1,270 | 0.1% | 179 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.