Gene
NFATC4
nuclear factor of activated T cells 4
Explore in graph →CI-GENE-00016670HGNC:7778 ENSG00000100968 NCBI 4776 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Thyroid Carcinoma (TCGA, Firehose Legacy) thca_tcga | Thyroid Gland Papillary Carcinoma | Ssm | 3 | 405 | 0.7% | 138 | cbioportal |
| Acute Myeloid Leukemia (OHSU, Cancer Cell 2022) aml_ohsu_2022 | Acute Myeloid Leukemia | Ssm | 6 | 903 | 0.7% | 87 | cbioportal |
| Papillary Thyroid Carcinoma (TCGA, Cell 2014) thca_tcga_pub | Thyroid Gland Papillary Carcinoma | Ssm | 3 | 496 | 0.6% | 136 | cbioportal |
| Pediatric European MAPPYACTS Trial (Gustave Roussy, Cancer Discov 2022) pancan_mappyacts_2022 | unmapped | Ssm | 1 | 674 | 0.1% | 83 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.