Gene
MYH3
myosin heavy chain 3
Explore in graph →CI-GENE-00015983HGNC:7573 ENSG00000109063 NCBI 4621 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (10)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Count Me In (CMI): The Angiosarcoma (ASC) Project CMI-ASC | Angiosarcoma | Ssm | 5 | 36 | 13.9% | 74 | gdc |
| Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017 | Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type | Ssm | 2 | 16 | 12.5% | 40 | cbioportal |
| Esophageal Cancer-TRAP Project (MSK, Lancet Oncol 2020) egc_trap_msk_2020 | Gastroesophageal Junction Adenocarcinoma | Ssm | 3 | 31 | 9.7% | 95 | cbioportal |
| The Angiosarcoma Project (Provisional, July 2020) angs_painter_2020 | Angiosarcoma | Ssm | 7 | 83 | 8.4% | 116 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.