Gene
MUTYH
mutY DNA glycosylase
Explore in graph →CI-GENE-00015923HGNC:7527 ENSG00000132781 NCBI 4595 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (29)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28373299
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 5 | 38 | 13.2% | 40 | cbioportal |
| Prostate Adenocarcinoma (MSK, Cancer Cell 2010) prad_mskcc | Prostate Adenocarcinoma | Ssm | 1 | 9 | 11.1% | 103 | cbioportal |
| Cutaneous Squamous Cell Carcinoma (DFCI, Clin Cancer Res 2015) cscc_dfarber_2015 | Skin Squamous Cell Carcinoma | Ssm | 3 | 29 | 10.3% | 179 | cbioportal |
| Malignant Peripheral Nerve Sheath Tumor (MSK, Nat Genet 2014) mpnst_mskcc | Malignant Peripheral Nerve Sheath Tumor | Ssm | 1 | 15 | 6.7% | 13 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.