Gene
MKRN3
makorin ring finger protein 3
Explore in graph →CI-GENE-00014640HGNC:7114 ENSG00000179455 NCBI 7681 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34358469
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Squamous Cell Carcinoma (CPTAC, Cell 2021) lusc_cptac_2021 | Lung Squamous Cell Carcinoma | Ssm | 12 | 108 | 11.1% | 118 | cbioportal |
| Lung Squamous Cell Carcinoma (CPTAC GDC, 2025) lusc_cptac_gdc | Lung Squamous Cell Carcinoma | Ssm | 11 | 110 | 10% | 126 | cbioportal |
| Myelodysplasia (UTokyo, Nature 2011) mds_tokyo_2011 | Myelodysplastic Syndrome | Ssm | 1 | 29 | 3.4% | 136 | cbioportal |
| Pancreatic Cancer (CPTAC GDC, 2025) pancreas_cptac_gdc | unmapped | Ssm | 4 | 181 | 2.2% | 132 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.