Gene
MCC
MCC regulator of Wnt signaling pathway
Explore in graph →CI-GENE-00012194HGNC:6935 ENSG00000171444 NCBI 4163 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adrenocortical Carcinoma (TCGA, Firehose Legacy) acc_tcga | Adrenal Cortical Carcinoma | Ssm | 7 | 90 | 7.8% | 153 | cbioportal |
| Pediatric Preclinical Testing Consortium (CHOP, Cell Rep 2019) pptc_2019 | unmapped | Ssm | 12 | 261 | 4.6% | 158 | cbioportal |
| Cystic Tumor of the Pancreas (Johns Hopkins, PNAS 2011) pact_jhu_2011 | Pancreatic Mucinous Cystic Neoplasm | Ssm | 1 | 32 | 3.1% | 200 | cbioportal |
| Prostate Adenocarcinoma (TCGA, Firehose Legacy) prad_tcga | Prostate Adenocarcinoma | Ssm | 8 | 499 | 1.6% | 178 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.