Gene
MBD5
methyl-CpG binding domain protein 5
Explore in graph →CI-GENE-00012164HGNC:20444 ENSG00000204406 NCBI 55777 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26683228
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Uveal Melanoma (QIMR, Oncotarget 2016) um_qimr_2016 | Uveal Melanoma | Ssm | 1 | 26 | 3.8% | 124 | cbioportal |
| Prostate Adenocarcinoma (SMMU, Eur Urol 2017) prad_eururol_2017 | Prostate Adenocarcinoma | Ssm | 2 | 65 | 3.1% | 46 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, Cell 2017) pcpg_tcga_pub | unmapped | Ssm | 2 | 178 | 1.1% | 150 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, Firehose Legacy) pcpg_tcga | Central Nervous System Neuroepithelial Neoplasm of Uncertain Origin | Ssm | 2 | 184 | 1.1% | 199 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.