Gene
MACROD2
mono-ADP ribosylhydrolase 2
Explore in graph →CI-GENE-00011793HGNC:16126 ENSG00000172264 NCBI 140733 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 27749842
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Urothelial Carcinoma (Cornell/Trento, Nat Gen 2016) blca_cornell_2016 | Bladder Urothelial Carcinoma | Ssm | 13 | 72 | 18.1% | 37 | cbioportal |
| Prostate Adenocarcinoma (Fred Hutchinson CRC, Nat Med 2016) prad_fhcrc | Prostate Adenocarcinoma | Ssm | 9 | 141 | 6.4% | 107 | cbioportal |
| Pediatric Ewing Sarcoma (DFCI, Cancer Discov 2014) es_dfarber_broad_2014 | Ewing Sarcoma | Ssm | 4 | 107 | 3.7% | 132 | cbioportal |
| Acute Leukemias of Ambiguous Lineage (TARGET GDC, 2025) alal_target_gdc | Acute Leukemia of Ambiguous Lineage | Ssm | 3 | 123 | 2.4% | 76 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.